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IMAGE SOURCE:CDC PHIL Technician performing Western Blot testing. Antigens if present will bind and be detected.

Contract Laboratory.com has received the following incoming Preclinical Laboratory Test Requests which need to be fulfilled ! These Preclinical Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational corporations to government agencies actively seeking Preclinical laboratories to perform their Preclinical laboratory testing and research. If your Laboratory receives Laboratory Test Requests that it can not fulfill, please refer them to us! If you have questions, please e-mail us or call 403-770-1992 .

Incoming Preclinical Laboratory Test Requests
No.
Preclinical Testing or preclinical Description
status
10-02163 UK Preclinical Contract Research Organization needed for preclinical study: Franz Diffusion Cell, to compare release profile of a particular known species ( read more ).....
10-02161 CHINA SFDA,FDA,GLP,USP,ASTM,ISO Preclinical Contract Research Organization needed to test the biocompatibility for medical devices such as stent or blood pooling bag. ( read more ).....
10-02134 USA FDA Preclinical Contract Research Organization needed to test 14 rodents (rats) injected once under anesthesia(gas isofluorane), monitored for 30 days. Blood and urine collection x 4 (baseline, and 2hrs, 15days, 30 days post injection). Biopsy at day 15, tissue procurement at day 30. ( read more ).....
10-02130 Preclinical Contract Research Organization needed for testing of pharmaceutical compound in a rat model of kidney transplantation modelling chronic allograft nephropathy ( read more ).....
10-02129 PA, OH, MD Preclinical Contract Research Organization needed to conduct Large Scale Chronic and Acute Bioassays ( read more ).....
10-02124 Preclinical Contract Research Organization needed for toxicology study for tumor promotion -we have isolated new phorbol esters which we suppose to cause tumor promotion similar to regular positive control (TPA) used for the studies. Please give us a feedback with other end parameters we could study during experiment. ( read more ).....
10-02121 Preclinical Contract Research Organization needed for testing the effect of one of our drugs in the Concanavalin A induces acute hepatitis model ( read more ).....
10-02120 Preclinical Contract Research Organization needed to test the effect of one of our drugs in an animal model (mice) of Uveitis ( read more ).....
10-02106 Preclinical Contract Research Organization needed for testing the effect of drugs in development for lowering IOP and protecting the optical nerve in rodent models for Glaucoma ( read more ).....
10-02102 Preclinical Contract Research Organization needed for in vivo corenal angiogenesis assay ( read more ).....
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10-02073 Europe Preclinical Contract Research Organization needed for efficacy studies in rabbit for new heparin product of non-mammalian origin ( read more ).....
10-02043 Preclinical Contract Research Organization needed for testing gastric emptying in monkey in order to evaluate drugs on this parameter. ( read more ).....
10-02022 USA/India FDA GMP/GLP Preclinical Contract Research Organization needed for in-vitro drug release analysis of medical device, Stability Studies for medical devices, Sample as required for testing. ( read more ).....
10-02018 FDA Preclinical Contract Research Organization needed for biocompatibility testing on a peripheral catheter product line. How many samples are needed for each test and the turn around time for each test (regular and expedited)?  Cytotoxicity  Sensitization  Irritation or intracutaneous reactivity  System toxicity (acute)  Subchronic toxicity (subacute toxicity)  Genotoxicity  Haemocompatibility ( read more ).....
Mouse model aging, indflueza vaccine, ( read more ).....
10-02011 Preclinical Contract Research Organization needed for IgM and IgG antibody test designed to identify the active or remote presence of a specific Trematode infection in the human body that has not yet been developed. ( read more ).....
10-01996 Leading manufacturer of Ayurvedic herbal medicine needs Preclinical Contract Research Organization for testing a new medicine for ANTI HIV. ( read more ).....
10-01963 Preclinical Contract Research Organization needed to measure Resveratrol in mice plasma and tissues after gavage feeding. ( read more ).....
10-01957 USA Preclinical Contract Research Organization needed to test compounds against HIV in cell culture. ( read more ).....
10-01951 USA GMP Preclinical Contract Research Organization needed for Prothrombin clotting assay. Use of Coag A Mate(registered) Instrumentation ( read more ).....
10-01947 Nigeria Preclinical Contract Research Organization needed for In vitro toxicology testing especially in Plants used for alternative medicine ( read more ).....
10-01940 Preclinical Contract Research Organization needed for radioactive (14C) ADME studies in Rat, Dog and Monkey ( read more ).....
10-01939 USA/UK Preclinical Contract Research Organization needed for rat gastric emptying ( read more ).....
10-01936 USA FDA ICH Preclinical Contract Research Organization needed to conduct preclinical studies to support a Phase 1 IND filign for a new drug. We need genotoxicity, mutagenicity, repeat dose toxicology in 2 species (rodent and nonrodent) with toxicokinetics and histopathology, and safety pharmacology to support a chronic long-term use in human patients. ( read more ).....
10-01932 Preclinical Contract Research Organization needed for in vitro oncology assays, cell migration assays (eg. Boyden chamber), MMP zymography, cell cycle analysis. If you are able to provide analysis, please advise if you have glioma cell lines in house that you could utilize for the assays? I am interested in your capabilities with respect to the above, and the timeline and costs if we were to request such assays. ( read more ).....
10-01913 Non GLP Preclinical Contract Research Organization CRO needed for chemical ingestion toxicity study for preclinical testing: 10 treated animals, 10 control animals, 14 day observation phase. non-glp... primary skin: 3 rabbits + primary eye: 3 rabbits + acute oral tox: limit 5000 ( read more ).....Closed
10-01899 USA/China GLP Preclinical Contract Research Organization needed for 2 anilam tox studies of intanasal tox, 1 non-rodent; BID treatment for 4 weeks ( read more ).....
10-01893 Canada Preclinical Contract Research Organization needed for measurement of the small molecule metabolite 2-hydroxyglutarate in sera, cell and tissue extracts. Potential for hundreds of samples over the next few years. Published LC/MS and GC/MS protocols available. ( read more ).....
10-01885 Pharmaceutical Company needs Preclinical Contract Research Organization to perform IC50 determinations of compounds designed for against human prostaglandin D2 synthase (PGD2S) ( read more ).....
10-01884 Europe, USA or UK Preclinical Contract Research Organization needed for full binding receptor profile. ( read more ).....
10-01878 Preclinical Contract Research Organization needed to do a study with human cardiac myocytes ( read more ).....
10-01876 GLP Preclinical Contract Research Organization needed for toxicology testing: OECD 437,438; and in vitro EpiSkin, EpiDerm and SkinEthic ( read more ).....
10-01849 Non GLP Preclinical Contract Research Organization needed to test mitrochondrial toxicity of nucleoside analogs ( read more ).....
10-01823 Europe Preclinical Contract Research Organization needed for xenograft testing. ( read more ).....
10-01812 Bioresorbable Medical Device Company needs GLP Preclinical Contract Research Organization in Europe/Netherlands for development phase for one of our existing product. Regarding the same we need to do some in vivo(rat model) study for which we need to have GLP certified labs. The study is intended as a short term study. ( read more ).....
10-01739 Philippines Preclinical Contract Research Organization needed for in-vitro spf testing ( read more ).....
10-01730 Preclinical Contract Research Organiztion needed to test a vitamin supplement to evaluate the effectiveness of this product - (www.bite-amins.com) which 1) helps keep mosquitoes from biting, and 2) reduces the bite's allergic reaction. ( read more ).....
10-01672 Europe preclinical Contract Research Organization needed for testing a SCID mouse model for Psoriasis: human psoriatic skin is grafted onto the mouse and then treated topically by our compound ( read more ).....
10-01662 Preclinical Contract Research Organization needed for testing a vaccine that by Plasmodium berghei challenge of mice. Testing 5-20 groups of 5 mice each. Readouts for parasitemia and store blood for ELISA. May have small ELISA study done first. ( read more ).....
10-01652 Preclinical Contract Research Organization needed for animal testing (mice and rabbits) in preparation for an IND for human testing. My company is working with Dr. Robert S. Fuller at the University of Michigan Ann Arbor to help develop his patented therapeutic for curing Anthrax infection. ( read more ).....Closed
10-01651 GMP Preclinical Contract Research Organization needed for avian extraneous agent testing on seeds according to European Pharmacopoeia 2.6.24. ( read more ).....
10-01637 Preclinical Contract Research Organization needed for testing a natural product that is a remedy for herpes virus 1 & 2 which was tested very successfully in its original form by Nottingham University. We have now changed the formulation somewhat and would like to test this new formula against the virus. We have 3 formulations which we will need testing. an oil , an ointment and a cream. ( read more ).....
10-01633 Preclinical Contract Research Organization needed for study. Before we test bioavailability in humans, we would like to compare the new galenic form after single dose oral administration of 30 mg methylphenidate hydrochloride in the fed state in pigs with our marketed galenic form (Medikinet retard). The aim of the study will be to compare bioavailabilities (rate and extent of absorption) in fed state of the two formulations tested. The AUC curve over 24 hours should be shown with close monitori ( read more ).....
10-01630 Preclinical Contract Research Organization needed for in-vitro testing to evaluate the efficacy of an anti-mycotic compound for the care of infected nails. ( read more ).....
10-01627 GLP FDA Preclinical Contract Research Organization needed for toxicology and safety pharmacology in dogs, 28 day repeat dose study in dogs, HeRG study in dogs. ( read more ).....Closed
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10-01598 Preclinical Contract Research Organization needed for preclinical study using models of spreading cortical depression either in vivo or in brain slices with which to test our compound. ( read more ).....
10-01597 Preclinical Contract Research Organization needed for influenza viral challenge testing. Mice will be vaccinated with a supplied subunit influenza vaccine and tested for protective immunity by challenge with live influenza virus (A/PR/8/34, or similar strain). The experiment will require less than 50 mice. Serum samples will be required (3 time points). ( read more ).....
10-01594 Germany GLP Preclinical Contract Research Organization need for clinical trial cytokine analysis with fast turnaround time. ( read more ).....
10-01593 UK UKAS Preclinical Contract Research Organiztion needed to use a gut model in order to test the effectiveness of a biocidal technology against C.diff spores that have passed into / through the human digestive tract. The biocidal technology is reported to be sporistatic and attaches to the outside of a C.diff spore coat. The biocides proposed mechanism of action is that it will prevent c.diff infection by causing cell lysis at the point of c.diff germination. My research question is: ( read more ).....
10-01591 Non GLP Preclinical Contract Research Organiztion needed for preclinical pharmacology study using mouse GvHD model. ( read more ).....
10-01587 Europe/USA Non-GLP Preclinical Contract Research Organization needed for screening new substances for anti-HBV activity. The selected compounds will be studies in various resistant mutant strains and in different cell lines. And the mechanism studies and combination studies will follow. ( read more ).....
10-01584 EU GLP Preclinical Contract Research Organization needed for Preclinical Toxicology Study for a new Herbal drug product which is developed in our company. Need to get documentation for registration of this new drug in EU. ( read more ).....
10-01576 GLP ISO Preclinical Contract Research Organization needed for product PMMA ring segment Studies - Maximization test - Systemic Toxicity Test - Pyrogen Test - Intracutaneous Test - Genotoxicity test - Ames and In Vitro Chromosomal Aberration Study in Mammalian Cells - Cytotoxicity Test - Implantation Test (12Week) Method ISO 10993 last version. Please add the following requirements for the realization of the test: - The Intracutaneous Test, Systemic Toxicity Test and Maximization Test should be p ( read more ).....
10-01550 USA FDA Preclinical Contract Research Organization needed to provide clinical trial services for the company product - home based Hair Regrowth treatment so that our product can be registered in USA FDA. ( read more ).....
10-01543 USA FDA GLP Preclinical Contract Research Organization needed for GLP Toxicology Studies: Rat - single adiministration (including toxic kinetics) Rat - multiple administration (including toxic kinetics, 2 weeks) Monkey - single administration (including toxic kinetics) Monkey - multiple administration (including toxic kinetics, 2 weeks) Sentral nerve system (Rat) Respiratory system (Rat) Cardiovascular (Monkey) hERG Ames test ( read more ).....
10-01533 USA GLP Preclinical Contract Research Organization needed for: General toxicity test Safety pharmacological test Genetic toxicity test ( read more ).....
10-01532 India Preclinical Contract Research Organization needed for antileishmanial activity of newly synthesized compounds. ( read more ).....
10-01511 Preclinical Bioanalytical Laboratory needed for pre-GMP protein purification testing, cellular expression testing, bioassay testing ( read more ).....
10-01502 Northeast USA(NH/MA Area) FDA, ASTM, ISO, GLP Preclinical Contract Research Organization needed for R&D Feasibility Study with Bovine Blood; ~20-25 samples for hemolysis evaluations ( read more ).....
10-01494 Europe GLP/GMP Preclinical Contract Research Organization needed for fixed or frozen animal organs from preclinical studies (heart, lung, liver, brain...) to be sectioned (2-5µm) and stained classically for pathology and also stained with multiple fluorescently labeled antibodies for colocalization analysis. The fluorescence microscopy analysis can be performed in our laboratories. ( read more ).....
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10-01482 USA GLP Preclinical Research Organization needed to test 16 samples for muscarinic receptor (acetylcholine) ( read more ).....
10-01477 FDA Preclinical Contract Research Organization needed to perform an ocular PK study comparing two different formulation (gel and eye drop)for topical application in monkeys. The major metabolite would need to be measured using LC/MS-MS (method can be transferred) in ocular tissues (retina, choroid, vitrous) at different time points following application. Need quote for single and repetitive (5 days) dosing. ( read more ).....
(1) Absorption, Metabolism of Retinol in Epidermis (Human in vitro) (2) Conversion Rate of Retinol to Retinoic Acid (Human in vitro) (3) Retinoic acid induced HB-EGF expression, Keratinocyte proliferation. ( read more ).....
10-01446 Preclinical Contract Research Organization needed for the following: (1) Absorption, Metabolism of Retinol in Epidermis (Human in vitro) (2) Conversion Rate of Retinol to Retinoic Acid (Human in vitro) (3) RA induced HB-EGF expression, Keratinocyte proliferation ( read more ).....
10-01438 FDA Preclinical Contract Research Organization needed for in vivo juvenile rat bone growth study to test small Prostaglandin derivative molecule and metabolite. F1 generation only, Days 21 to 105 post partum, inclusive with a 6 week recovery period. Analysis/imaging of bones and bone formation/resorbtion markers. ( read more ).....
10-01430 Preclinical Contract Research Organization needed to perform toxicology tests for riot control agents (CS, OC and HCE based products) which we have developed in our laboratory. Need to understand what effects are on humans and whether it is hazardous to human health or not. How many tests are there in your laboratory for long standing records and cumulative research on human effects of riot control agents. ( read more ).....
10-01404 Philippines, Asia, India Preclinical Contract Research Organization needed for In Vitro Sun Protection Factor (SPF) testing of at least 6 samples. ( read more ).....
10-01398 Preclinical Contract Research Organization needed for testing connective tissue growth factor approximately 20 subjects requiring CTGF measured at 2 interval during the study ( read more ).....
10-01385 USA Preclinical Contract Research Organization needed for Connective Tissue Growth Factor in study subjects with Diabetic Nephropathy (Type 2 Diabetes Mellitus) ( read more ).....
10-01382 Europe Preclinical Contract Research Organization needed for the following study: Methylphenidate (MPH) is a central nervous system stimulant used for treatment of Attention Deficit Hyperactivity Disorder (ADHD). Medice is developing modified release (MR) capsules. Before we test bioavailability in humans, we would like to compare the new galenic form after single dose oral administration of 30 mg methylphenidate hydrochloride in the fed state in pigs with our marketed galenic form (Medikin ( read more ).....Closed
10-01372 Southern California Preclinical Contract Research Organization needed for observation of subcutaneous tissue via rodent dorsal skinfold chamber ( read more ).....
10-01368 Preclinical Contract Research Organization needed that has an appropriate animal model to determine ADCC effect for Mab development. We were told that SCIDhu with human PBMC would be one of options. Any other models would be welcome. ( read more ).....
10-01367 Preclinical Contract Research Organization needed for a monkey efficacy model for thrombocytopenia. ( read more ).....
10-01366 Preclinical Contract Research Organization needed to conduct an efficacy evaluation using appropriate animal models in vivo of collyrium for the drug development. ( read more ).....
10-01359 GLP Analytical Chemistry Laboratory needed for validated analysis of bromide by IC for preclinical and clinical plasma analysis ( read more ).....
10-01354 UK EN Preclinical Contract Research Organization needed for testing effectiveness of a new disinfectant against common viruses including Hepatitis B if possible. ( read more ).....
10-01316 USA, Asia, UK, Europe FDA, GLP Preclinical Contract Research Organization needed for Preclinical GLP Studies: Acute Oral toxicity in Rats Sub-acute, Chronic Oral toxicity, Skin sensitization, dermal irritation, dermal toxicity ( read more ).....
10-01311 Preclinical Contract Research Organization needed for preclincial pain study, experiment rodent model of pain (neuropathic pain like oxaliplatine). Need Urgent reply please. ( read more ).....
10-01294 Preclinical Contract Research Organization needed to evaluate multiple compounds in model(s) of acute lung injury. ( read more ).....
10-01288 France, Germany, Switzerland preferred EMEA Preclinical Contract Research Organization required for preclinical toxicity testing and safety of a recombinant BCG strain (GMP quality) in the treatment for non-muscle invasive bladder cancer. ( read more ).....
10-01287 USA Preclinical Contract Research Organization needed to expose Long Evans male rats to two doses of an OP pesticide plus a vehicle control (subcutaneous delivery, daily injections) for 21-days. At the end of the exposure period, perform contextual fear conditioning and record results. A separate cohort of animals will be simultaneously exposed to the same pesticide doses (plus control) in parallel for 21-days, however there will be no fear conditioning performed on these animals. At the end of ( read more ).....
10-01277 NE USA GLP Preclinical Contract Research Organization required for Human Lymphocyte Chromosome Abberation Test ( read more ).....
10-01254 Preclinical Contract Research Organization required to quantify how much silicone is deposited on hair from shampoos; there are 4 shampoos to be tested. The hair type to be used is probably virgin hair. ( read more ).....
10-01242 Preclinical Contract Research Organization needed for testing hypoxic rat model of pulmonary arterial hypertension ( read more ).....
10-01241 Pharmaceutical Company in Italy requires Preclinical Contract Research Organization to perform a PK study of a drug as a topical creme to be applied on the skin in Göttingen Minipigs. Concentrations to be measured by a Dermal Microdialysis Sampling Technique at different times from application of the creme. ( read more ).....
10-01221 American Pharmaceutical Company requires a Preclinical Contract Research Organization for conventional carcinogenicity testing, almost certainly in the mouse and rat but possibly in the hamster instead of one of those species. The drug is already approved for in use in man but full development requires the results of carcinogenicity testing for EU, US, Japanese and other agencies. It is not genotoxic in relevant tests. Methods exist for its analytical control, its stability is well established a ( read more ).....
10-01200 USA GLP Preclinical Contract Research Organization needed for GLP Study, multi-plex pcr testing on single plasma sample for following viruses: Adenovirus, herpesviruses (CMV,HSV-1 and -2,VZV, EBV, HHV6, and HHV8), JCV, BKV, and HPV. Please provide cost estimate. ( read more ).....
10-01182 USA CLIA Preclinical Contract Research Organization required to process 8 SnP genetic test. Assay provided. ( read more ).....
10-01181 Preclinical Contract Research Organization required to test different hormones in Rabbits, male and female. We can supply the serum and or blood. ( read more ).....
10-01179 UK ISO 9001 or ISO 13485 GLP Preclinical Contract Research Organization required to supply adenovirus and after exposure to disinfection agent. perform a viral count to test disinfection efficacy. ( read more ).....
10-01172 Preclinical Contract Research Organization required for an efficacy model for psoriasis to check a a topically administered drug candidate. Suitable, in vitro, human skin models may also be considered ( read more ).....
10-01126 USA FDA GMP Preclinical Contract Research Organization needed for Tox studies of radiotherapeutics to simulate a safe dose in humans ( read more ).....
10-01079 Preclinical Contract Research Organization needed for Non-GLP Preclinical Study, chronic obstructive pulmonary disease (COPD) animal model ( read more ).....
10-01047 AAALAC Preclinical Contract Research Organization needed for biomarker Skin microdialysis in laboratory animals ( read more ).....
10-01025 Preclinical Contract Research Organization needed for Dermal sensitivity and irritation testing in transdermal spray treatment. Main study 20 guinea pigs (10T/10C) ( read more ).....
10-01011 USA Preclinical Contract Research Organization, Histology and Pathology Laboratory needed for TUNEL staining of various mouse organs ( read more ).....
10-01005 USA FDA GMP Preclinical CRO needed for Acute and subchronic (28days) toxicity studies; ADME studies ( read more ).....
10-00967 India Preclinical CRO needed for genotoxicity testing, in vivo genotoxicity of orthodontic wires on buccal cells with micronucleus and comet assay. ( read more ).....
10-00966 Large Pharmaceutical Company needs Preclinical CRO needed to perform IC50 determinations in LPS stimulated PBMC with TNFalpha as readout ( read more ).....
10-00955 Non-GLP preclinical contract research organization needed for non-GLP study rabbit spinal fusion study ( read more ).....
10-00943 Preclinical Contract Research Organization needed for USP Product Safety Studies (on mice) and Antigenic impurities (on Guinea pigs) for Dextran 40 according to USP 32. This is a one time event and between three and six samples will be tested ( read more ).....
10-00939 University needs California FDA GMP Preclinical Laboratory needed for FDA immunogenicity studies ( read more ).....
10-00936 USA FDA GLP Preclinical Contract Research Organization needed for Toxicity evaluation for FDA NDA: (toxicology and toxicokinetics) in rats is needed to meet 21 CFR 312.23. Quotations required within 24h. ( read more ).....Closed
10-00930 India FDA GLP Preclinical Contract Research Organization needed for GLP Study, nasal spray Evaluation for Particle size 2. Droplet size 3. Size distribution 4. Spray pattern 5. Plume geometry. ( read more ).....
10-00904 Pharmaceutical Preclinical Contract Research Organization needed for toxicity study for a liquid sample 1. Skin Irritation test. 2. Oral injection test 3. Eye Irritations test. 4. Any Allergies test. Also quote for the same with the volume of sample required for the testings and duration of time required for the test reports to be expected. ( read more ).....
10-00884 Midwest USA FDA GLP Preclinical Contract Research Organization needed for GLP Preclinical Studies, Acute porcine general and thoracic surgery ( read more ).....
10-00869 Toronto FDA, GLP pharmaceutical laboratory needed for preclinical studies: safety, formulation and preformulation study ( read more ).....Closed
10-00868 FDA GLP Bioanalytical Preclinical Central Laboratory needed for Pharmacokinetic Study, plasma testing of PK samples for analysis in about 200 plasma samples from a clinical trial which are to be analyzed by LCMS for a small molecule. Data analysis optional. ( read more ).....
10-00833 US Preclinical Laboratory (preferred US) needed for hair growth efficacy tesing in vivo, especially eyebrow ( read more ).....CLOSED
10-00832 AAALAC preclinical contract research organization (US preferred) needed for hair growth efficacy testing, especially eyebrow growth. ( read more ).....
10-00831 Preclinical Laboratory to test efficacy evaluation of eyelashes restorer in an appropriate animal model. We are not sure what kinds of animal models could be applicable for this eyelashes restorer. Please advise on an appropriate animal model, outline, and price ( read more ).....Closed
10-00830 Non European Union OECD, FDA GLP preclinical laboratory to conduct photo-sensitization in mice, i.e., photo-LLNA ( read more ).....
10-00762 US GMP preclinical laboratory to test compounds for effects on ciliary beat frequency of ear (Eustachian tube) mucosa of animals. ( read more ).....Closed
10-00731 Preclinical laboratory needed for estimation of oxygen in a product. Determination of penetration of oxygen into the skin. 3.Determination of increased ceel activity due to oxygen. 4.Role of oxygen in trasportation of active molecule. ( read more ).....Closed
10-00687 Preclinical COntract Research Organization needed for non-clinical efficacy studies of anti-HIV molecules (non clinical virology)anti-HIV small molecule screening in resistant strains, Elucidation of mechanims of action, invitro drug comibination studies, preclinical developmet of anti-HIV molecules ( read more ).....
10-00674 Preclinical Contract Research Organization needed for pharmaceutical efficacy testing of a compound in an EAE model of multiple sclerosis ( read more ).....Closed
10-00580 Preclinical Contract Research Organizaiton needed for proof of concept study for two of our therapeutic vaccine targeting inflammatory pathways in a preclinical (mouse) model for chronic obstructive pulmonary disease ( read more ).....
10-00577 Preclinical Laboratory needed for Tumor Angiogenesis inhibition activity testing of compounds, Cell migration or inhibition assays, CAM assay, tube formation, aorta ring assay, etc ( read more ).....Closed
10-00573 USA Preclinical Contract Research Organization needed for Preclinical Study, Blood pressure lowering effect in SHR rats 2) Bronchospastic effect in guinea pigs (anaphylactoid reactions) 3) Thrombogenic effect in rabbits ( read more ).....
10-00571 Europe FDA GLP Preclinical Toxicology Laboratory needed for GLP Study, Acute oral toxicity new drug 2) 28-days repeated dose oral toxicity generic drug 3)Sensitization ability of farmaceutical composition of two well known drugs ( read more ).....Closed
10-00554 Canada FDA GMP Preclinical Toxicology Laboratory needed for study with recombinant Sendai virus based vectored vaccine. Sendai virus is a mouse pathogen although the strain we are using is attenuated it still causes bronchial pneumonia in rodents. No effect in rabbits and hopefully none in higher order mammals such as NHP or humans. We need a GLP tox lab that is prepared to conduct studies in mice, rabbits and NHPs. The studies would involve assessing the virulence (pathogenicity), virus gro ( read more ).....Closed
10-00548 Preclinical Contract Research Organization needed for in vivo skin penetration of drug into normal and psoriatic-like pig skin ( read more ).....
10-00541 Europe FDA GLP Preclinical Toxicology Laboratory needed for Preclinical Study, In vivo rat, various standrd biochemical assays, inflammatory mediatotrs and histology ( read more ).....Closed
10-00534 USA Preclinical Contract Research Organization needed for intravenous immunoglobulin (IVIG) In vivo and in vitro efficacy studies by mouse protection testing using Klebsiella pneumoniae and Streptococcus pneumoniae and in vitro by opsonization and protein A addinity chromatography ( read more ).....
10-00520 Preclinical Contract Research Organization needed for preclinical study animal model of scleroderma ( read more ).....
10-00442 Non GLP Preclinical Contract Research Organization needed for Non-GLP testing compounds in hypertension rat model" ( read more ).....
10-00434 Preclinical Contract Research Organization needed for IC50 evaluations of anti-HIV and anti-HCV drugsUsing PBMC for anti-HIV determinations and replicon or HCVcc systems for anti-HCV evaluation ( read more ).....Closed
10-00433 Preclinical Contract Research Organization needed for exploratory research micro-surgery on rat model, Hyperinsulinemic Euglycemic clamp is preferred. Collect and analyse of blood analytes, ( read more ).....Closed
10-00403 Preclinical GLP Contract Research Organization needed for testing a biopharmaceutical cell based therapy on rats and mice. The aim of the study is to cause a heart failure, to inject viable cells into the infarcted areas and do the follow-up of the experiment (echography, ...). ( read more ).....
10-00393 Preclinical OECD, GLP Contract Research Organization needed for testing toxicity vitro, vivo. ( read more ).....Closed
10-00369 Preclinical Contract Research Organization needed for short term 2-3 week COPD lung model testing of a small molecule anti-inflammatory. ( read more ).....
10-00322 FDA, USP Preclinical Contract Research Organization needed for testing DNA vaccine. Host Cell Item Test: DNA, RNA, Protein % Supercoiled plasmid DNA, Potency Bioactivity, Other tests. ( read more ).....Closed
10-00318 Singapore GLP Preclinical Contract Research Organization needed for toxicology testing of a dermal patch formulation applied semi-occlusive once daily to mini pigs. ( read more ).....Closed
10-00304 Preclinical Contract Research Organization needed for testing DNA vaccine products to meet different countries or regions individual specifications. For a biopharmaceutical manufacturer in DNA vaccine and whose project is under preclinical animal work. ( read more ).....
10-00283 USA or North America preclinical contract research organization needed for proof of concept, celluar molecular testing animal model of periodontal disease. ( read more ).....
10-00277 FDA GLP Preclinical Contract Research Organization needed for pneumococcal polysaccharide vaccine develoments, impurities like protein nucleic acid and C polysaccharide. ( read more ).....Closed
10-00274 USA Preclinical Contract Research Organization needed for preclinical study with Electrodes and brain drug delivery systems /implants with feedback control and release of drug/hormones effecting the hypothalamic pituitary axis - for testing on brain tumor/ hemangiopericytoma/other brain tumor(s) - as an adjunct to treatment or prevention of growth of these and other tumors in animals, and or humans. Research would be aimed at optimising haemostasis- with anticipated general and specific benefi ( read more ).....
10-00266 European non-GLP Preclinical CRO needed for testing antifungals and antibacterial by vaginal delivery. ( read more ).....
10-00255 European FDA GMP, GLP UKAS Preclinical Bioanalytical Laboratory needed for bioassay testing of biopharmaceutical products. ( read more ).....
10-00248 Preclinical Laboratory for preclinical efficacy trials to test water filters that produce a biologically active water on mice. ( read more ).....
10-00244 Non-GLP Preclinical Laboratory needed for in vivo efficacy study of an anti-cancer drug with mice transplanted with human low-grade NHL cells (DOHH-2, KARPAS-422, or WSU-NHL) or MCL cells (Z-138,REC-1, or JEKO-1). ( read more ).....
10-00220 Non-GLP Preclinical Laboratory needed for cell toxicity testing, feasibility of lymphoma-cell growth inhibition test to determine IC50 of an anticancer drug. JEKO-1, REC-1, DOHH-2 and WSU-NHL are considered as cell-lines of mantle-cell lymphoma and Low-grade NHL, and those cell-lines are available from DSMZ (or ATCC and ICLC for some). The study is needed for NDA in Japan urgently. I very appreciate if you would inform me of the estimate of the study and its shortest schedule until the avai ( read more ).....Closed
10-00218 Southern California FDA GLP Preclinical Toxicology Laboratory needed for toxicity, sensitization study (extract solution) using mouse local lymph node assay ( read more ).....Closed
10-00217 USA FDA GLP preclinical immunology Contract Research Organization needed for GLP Level immune response Vaccinia (MVA) titer ( read more ).....Closed
10-00207 Preclinical Bioanalytical laboratory needed for human apolipoprotein E quantitation on brain extracts ( read more ).....
10-00205 Preclinical Laboratory needed for toxicology testing, efficacy testing of feminime sanitary napkin with impregnated bio-ceramic. Our like to test if it can improve dysmonorrhea & vaginal white discharge. ( read more ).....Closed
10-00204 Preclinical Oncology Contract Research Organization needed for in vitro oncology evaluation using human lymphoma ( read more ).....Closed
10-00201 FDA GLP Preclinical Laboratory needed for Bioequivalence (BE) with Clinical Endpoint Study Design: Randomized, double blind, parallel, placebo-controlled in vivo ( read more ).....
10-00197 FDA GMP Preclinical Laboratory needed to study effects of linaclotide and a test compound on tight junction protein expression and gut permeability in a constipated diabetic pig model. Diabetic pig model can be produced by destroying pancreatic beta cells with streptozotocin or alloxan and constipation could probably be induced by loperamide or morphine. ( read more ).....Closed
10-00178 FDA GLP Preclinical Toxicology Contract Research Organizations CRO needed for GLP Preclinical Study 5 day continuous iv infusion in cynomolgus monkey. 5 high dose active and 2 placebo animals. 3 animals for 2 week retention. ( read more ).....Closed
10-00175 US Preclinical Contract Research Organization needed for In-Vivo Animal Studies " ( read more ).....
10-00152 USA Preclinical Contract Research Organization needed for preclinical testing of wound healing products in animal models ( read more ).....Closed
10-00138 FDA GLP Preclinical Contract Research Organization needed to analyze the effects of a small molecule compound and potentially its major metabolite on afferent activity in intestinal spinal and vagal afferents in an animal model ( read more ).....Closed
10-00102 Preclinical CRO needed with urease inhibition assay up and running to screen several compounds in vitro for urease inhibition. Must have up and running already ( read more ).....CLOSED
10-00092 Large Pharma needs Preclinical Contract Research Organization venous stasis (Wessler) model study in rats or mouse ( read more ).....
10-00046 Preclinical CRO Laboratory needed for testing novel small molecule in an animal model as a possible radiosensitizer in the treatment of brain metastases. ( read more ).....Closed
10-00027 Preclinical Laboratory needed for Pulmonary Inflammation Models (asthma model) allegen study Mouse strain (C57BL/6J) ( read more ).....
10-00020 Ireland Preclinical, Product Safety, Toxicology Laboratory needed for effectiveness, toxicity, safety. ( read more ).....Closed
09-2541 Europe Preclinical Laboratory needed for invivo and invitro assays on insulin. assays like receptor binding, cell based assays and evaluate toxicity in a repeated dose 4 week study in rats. toxicology ( read more ).....Closed
09-2492 Non-GLP Preclinical Contract Research Organization needed for tissue fibrosis and COPD/asthma compound effects studies in-vitro, ex-vivo and in-vivo assays assays: 1) Tissue fibrosis - ex vivo compound ability to reduce fibroblast capacity to contract free-floating collagen lattices - ex vivo compound ability to reduce a-smooth muscle actin gene expression - ex vivo compound ability to inhibit fibroblast motility - in vivo models for lung, skin, liver and kidney fibrosis primarily analy ( read more ).....Closed
09-2483 Preclinical CRO, molecular biology laboratory needed for ligand binding assay novel AT1 receptor antagonists, binding affinity and specificity for the AT1 receptor. As these drugs will be tested in rats, selectivity for AT1A versus AT1B and AT2 receptors needs to be elucidated. ( read more ).....
09-2471 Europe Preclinical Contract Research Organization need for product safety, animal trial is required that will assess the safety of a new angioplasty balloon in a comparative study against against a currently marketed balloon. Two/three pigs are required for the study, whereby femoral or iliac or carotid arteries will be dilated with the concept device and a control device. The vessels will be over-expanded to approximately 120 - 200 % of their original diameter. A left or right vessel will be ( read more ).....Closed
09-2468 Pharmaceuticals Preclinical Contract Research Organization needed for Pharmacokinetics Study, Two-Phase Cross-Over in Dogs - Live Phase only Study to utilize cross-over (oral + intravenous) pharmacokinetics in dogs 2. Study will utilize n=2 male beagle dogs per compound to be evaluated. Animals may be non-naïve, following suitable washout period. 3. We will send the compound (solid powder) and instructions for making formulations and dose to be administered. The formulation will be prepared by ( read more ).....Closed
09-2467 USA or Europe FDA GLP Preclinical Contract Research Organization needed 3 months animal study of stenting in 16 swine. The Study is beeing planned to commence in April. ( read more ).....
09-2454 FDA GLP AAALAC Preclinical Toxicology Laboratory needed for a 9-month oral toxicity study in dogs, including toxicokinetics and 4-week recovery assessment. Test article (small molecule, oil soluble) is an Investigational New Drug intended for antiviral treatment especially HIV-1 / AIDS. The methodology for determination of test article in dog plasma and, the methodology for determination of test article concentration in dosing formulation are readily available. ( read more ).....Closed
09-2448 Preclinical Contract Research Organization needed for efficacy study of Cytotec (Misoprostol) on Hair Follicles. It Appears It Is Administered 2 hours before chemotherapy to enhance Hair Follicles. It is also used for another medical purpose. ( read more ).....Closed
09-2446 Preclinical Toxicology Laboratory needed for Acute Inhalation Toxicity Study . ( read more ).....Closed
09-2433 Preclinical Laboratory needed for small molecule testing on animal model potential elderly animals or a strain that is prone to the condition, that develop bowel impaction with susceptibility for perforation or are simple prone for bowel perforations. We would like to test a small molecule compound and a comparator drug for their potential to increase or decrease bowel perforation when given topically at clinical and supratherapeutic doses. Please, let me know if you offer anything in that ( read more ).....Closed
09-2430 Preclinical Biomechanical Laboratory needed for ISO Orthopedic Implant Knee/Hip wear testing ISO 14243-1:2009 and ISO 14243-2:2009 2) Hip wear testing :ISO 14243-1:2009 ( read more ).....
09-2423 USA Preclinical Bioanalytical Laboratory needed to determine bismuth concentration in rat plasma. ( read more ).....Closed
09-2400 Europe FDA GLP Preclinical Laboratory needed for Insulin-stimulated glucose uptake assays (preferable on 3T3 L1 preadipocyte cell line)  Insulin receptor binding and dissociation studies (preferable on CHO.T cell line)  Receptor activity studies (e.g. insulin-stimulated tyrosine phosphorylation , activation of Akt, activation of glycogen synthase kinase, activation of Map kinase - immunoblotting)  IGF-1 receptor binding studies  Mitogenic potency (human o ( read more ).....
09-2389 USA Preclinical Laboratory needed for in vitro and in vivo efficacy and potency testing of erythropoietin as well as perform a standard toxicity panel that is acceptable by the FDA ( read more ).....
09-2374 FDA GMP Preclinical laboratory needed for small molecule study on opiod (morphin) induced analgesia (tail pinch method) and constipation (graphite marker transport) in a mouse model. We would also like to test the effect of methadon and a combination of methadon and the study drug on morphin-induced analgesia and constipation. ( read more ).....Closed
09-2372 EPA Preclinical Toxicology Laboratory needed for OPPTS 870 Toxicology guideline studies Acute Repeat Dose Carcinogenicity ( read more ).....
09-2362 North California GLP Preclinical Laboratory needed for Quantitative Whole Body Autoradiography (QWBA) on mouse- biodistribution of a radiolabeled nanocapsule ( read more ).....Closed
09-2358 FDA GLP preclinical toxicology laboratory needed for toxicity studies water soluble chemical entity (to be supplemented orally), We need contractual services to carry out these studies viz; animal toxicology, pharmacology, pharmacokinetics and/or related studies which are mandatory before getting approval for clinical trials. Also whether the data generated would be compliant to support the IND application as well? ( read more ).....Closed
09-2345 USA FDA GLP Preclinical Laboratory needed for Mouse tumor study with MS1 angiosarcoma cells to look for efficacy of anti-angiogenic drug. ( read more ).....
09-2341 India FDA GLP Preclinical Laboratory needed for Animal toxicity studies, pharmcokinetics water soluble chemical entity (to be supplemented orally), for which we have to perform the clinical trials. For this, pre-clinical toxicity studies need to be carried out by a GLP certified laboratory. Contractual services are required to carry out these studies viz; animal toxicology, pharmacology, pharmacokinetics and/or related studies which are mandatory before getting approval for clinical trials. ( read more ).....Closed
09-2314 FDA GLP Preclinical laboratory needed for multiple species preclinical studies: Oral LD50 mg/kg LC50 Inhalation LC50 mg/4 hours Intravenous injection for infectivity For Eco-toxicological testing Birds (2 species) Aquatic organisms (2 species) Aquatic invertebrate Algae Bees Representative natural enemies Earthworms or other relevant soil invertebrate (eg termites) Soil micro-organisms Representative non-target plant On the formulated product: Rat, Acute oral LD50 mg ( read more ).....
09-2310 Preclinical Toxicology Laboratory needed for anti-viral mitochondrial toxicity studies in both in vitro and in vivo conditions. This is an anti-hepatitis B compound. FDA requires mitochondrial tox studies before FIH study. ( read more ).....Closed
09-2307 California FDA GMP Preclinical Laboratory needed for Preclinical Validation Studies of a medical device in animal model. ( read more ).....Closed
09-2257 USA Product Safety Laboratory needed for preclinical study to be administered as a single, subcutaneous injection in dogs. Conduct initial Safety Study using following parameters: * 6 healthy lab dogs (M and F] * Administer single, dorsoscapular subcutaneous R-Gel Enro injection * Blood draw: Days 1, 2, 3, 5, 7 & 9 to measure plasma concentrations of enrofloxacin * Visual observations: injection site tolerance, adverse events, overall well being ( read more ).....Closed
09-2255 Non-GLP Preclinical laboratory needed for influenza virus challenge study H1N1 virus challenge study in an appropriate animal model we are looking for a laboratory who has already setup process for an chanllenge study with H1N1 virus. ( read more ).....
09-2242 Canada or US FDA GMP Preclinical Laboratory for Development, validation and GMP testing of antitoxin to diphtheria toxin using the standard guinea pig assay ( read more ).....Closed
09-2240 China FDA GLP Preclinical CRO needed for GLP preclinical toxicity study for vaccine ( read more ).....
09-2238 Preclinical laboratory needed for in-vitro testing of anti-H1N1 effect ( read more ).....
09-2231 USA FDA GLP preclinical laboratory needed for GLP Preclinical Studies, rat paw edema test and mouse ear swelling test ( read more ).....
09-2210 USA Preclinical laboratory needed for preclinical studies of compounds in rodent models of acute kidney injury ( read more ).....Closed
09-2176 Preclinical Contract Research Organization required for testing induction of lipogenesis in human HEPG2 cells ( read more ).....Closed
09-2166 Preclinical Contract Research Organization required for serum neutralization or other appropriate test, E. Coli antibodies, Some or all agglutinating factors: K99, Y, 31A, F41, K30, K35 for bovine serum or colostrom. ( read more ).....Closed
09-2158 FDA Preclinical Contract Research Organization required to test a set of small molecule compounds (prostaglandin like structure) on the following parameters: Activation of ClC-2 type ion channels (EC 50) Activation of BK type potassium channels (EC 50) Membrane potential Mitochondrial membrane potential Intracellular calcium changes Intracellular cAMP changes Prostaglandin EP/FP receptor activity (EC50/IC 50). ( read more ).....Closed
Dear ladies and gentlemen, We would like to test a set of small molecule compounds (prostaglandin like structure) on the following parameters: Activation of ClC-2 type ion channels (EC 50) Activation of BK type potassium channels (EC 50) Membrane potential Mitochondrial membrane potential Intracellular calcium changes Intracellular cAMP changes Prostaglandin EP/FP receptor activity (EC50/IC 50). Please, let me know if you offer such services. If yes, what would the price ( read more ).....Closed
Dear ladies and gentlemen, We would like to test a set of small molecule compounds (prostaglandin like structure) on the following parameters: Activation of ClC-2 type ion channels (EC 50) Activation of BK type potassium channels (EC 50) Membrane potential Mitochondrial membrane potential Intracellular calcium changes Intracellular cAMP changes Prostaglandin EP/FP receptor activity (EC50/IC 50). Please, let me know if you offer such services. If yes, what would the price ( read more ).....Closed
serum neutralizing activity in influenza microneutralization assay ( read more ).....Closed
09-2136 Preclinical Contract Research Organization required to test a concept for developing leukemia-specific molecular therapeutic methods. These methods take advantage of the unique disease-specific chromosomal translocations that underly the leukemogenesis. ( read more ).....Closed
Tumor model studies in mice testing our biocetical method in shrinking tumors ( read more ).....Closed
09-2131 USA AAALAC Preclinical Contract Research Organization needed to perform tumor model studies in mice, testing our biocetical method in shrinking tumors. ( read more ).....Closed
09-2128 non-GLP Preclinical Contract Research Organization required for efficacy studies - diabetes, pain and inflammation animal models ( read more ).....Closed
09-2126 USA GLP Preclinical Contract Research Organization required for the following: Physical examination - qualify the subject companion animals as healthy and cancer free; get body score/weight Laboratory tests: Hematology, blood chemistry, thyroid function tests, fecal examination, urinanalysis Blood collected and stored for genetic testing (aliquots) DNA Serum collected Tumor collected and cancer type verified ( read more ).....
09-2078 PRECLINICAL CONTRACT RESEARCH ORANIZATION REQUIRED FOR RABISE VIRUS TESTING ( read more ).....Closed
09-2075 Texas GLP Preclinical Contract Research Organzization required for PK/PD and acute toxicity studies needed for Gallium 68 labeled radiotracer in preparation for exploratory IND ( read more ).....
09-2073 GLP Preclinical Contract Research Organization required for Rabbit Vitreal Bioassay - Release assay for raw material for opthalmic use ( read more ).....Closed
09-2072 Preclinical Contract Research Organization required for honeybee analyses and testing. ( read more ).....Closed
09-2068 Preclinical Contract Research Organization required for determination of drug displacement or binding on GABA B receptor and the interaction with baclofen ( read more ).....Closed
09-2066 Preclinical Contract Research Organization required for testing using pulmonary arterial hypertension animal models ( read more ).....Closed
Wessler stasis test ( read more ).....Closed
09-2064 Preferably Europe GLP Preclinical Contract Research Organization needed for Wessler stasis test ( read more ).....
09-2057 USA GLP EPA Preclinical Contract Research Organization needed for HINI inactivation in vitro test ( read more ).....Closed
09-2056 Asia GLP EPA/OECD Preclinical Contract Research Organization needed for oncogenecity and cobmined chronic and oncogenicity testing. ( read more ).....Closed
09-2052 Preclinical Contract Research Organization required to vaccinate mice and then challenge with vaccinia virus. At first we would be looking at 20-50 mice for signs of disease, weight loss and death; blood work may be included, or at least blood samples may be stored. ( read more ).....
09-2050 Preclinical Contract Research Organization needed for Neuropharmacology testing for Multiple sclerosis, Alzheimer's disease and traumatic brain injury ( read more ).....Closed
09-2049 Preclinical Contract Research Organization needed for in vitro anti-H1N1 testing - We have a liquid form product need to test its activity. ( read more ).....Closed
09-2045 Preclinical Contract Research Organization need for study to determine the effect of oral glucosamine on degenerative disc disease in a rabbit model. There have been various studies which have shown that oral glucosamine may or may not be helpful in preventing progression of knee osteoarthritis. It has been postulated that the variability of the results may be partly due to the fact that in the U.S. glucosamine is considering a dietary supplement and thus content and purity vary markedly from di ( read more ).....Closed
09-2042 Preclinical Contract Research Organization needed for lead optimization of 50 compounds/week of in a human based cell line in vitro-asssay as for an example Hep G2 cells ? We are talking 50 compunds a week. ( read more ).....Closed
09-2037 Europe, USA, Asia, England Preclinical Contract Research Organization needed for In vitro assay - Hep G2 cells or other human cell line - cell viability - 50 leading small molecule compunds on weekly basis. ( read more ).....Closed
09-2025 ISO Preclinical Contract Research Organization required for the following antibody titre assays-serum and colostrum: (1) rotavirus (hemagglutination inhibition or equivalent), (2)coronavirus (serum neutralization or equivalent), (3) E. coli (some or all agglutinating/attachment factors: K99, Y, 31A, F41, K30, K35) ( read more ).....Closed
09-2013 Australia Preclinical Contract Research Organization needed for Cell Growth Test, Virus testing(BVD) and sterility testing on Animal Sera. ( read more ).....Closed
09-2010 FDA Preclinical Contract Research Organization needed to run tumoral xenograph studies in rodents using 4-h infusion to administer the drug. ( read more ).....Closed
09-2005 US Preferred Preclinical Contract Research Organization required for Ischemic limb model (rat), and myocardio-ischemic model ( read more ).....
09-1983 Preclinical Contract Research Organization required for determination of leathality of two formulations of a potential rat poison by intra-gastric administration ( read more ).....Closed
09-1974 Canada preclinical Contract Research Organization needed for screening 20 antiviral compounds in vitro (neuraminidase inhibition) tests. For several compounds related to Tamiflu(TM) ( read more ).....
09-1951 Biotechnology Company with cancer vaccine immune modulator needs Preclinical Contract Research Organization for tumor model studies in mouse with our compound as an adjuvant to a cancer vaccine. I can provide more details but for now we are thinking about simple primary B16 and lung metastasis B16 in C57Bl6 mice with a B16 cell lysate vaccine. ( read more ).....Closed
09-1947 non-GLP Preclinical Contract Research Organization required for animal models (e.g. mice or rat) for studying drug induced immunomodulation/immunosupression on a rather fundamental/principal level, i.e. it does not have to be a specific disease model. ( read more ).....Closed
09-1923 Preclinical Contract Research Organization required for Intratracheal Instillation in rats (two formulations, 5 rats each, total 10 rats), blood sampling 10 timepoints, testing by LC-MS ( read more ).....Closed
09-1922 FDA and GLP Preclinical Contract Research Organization needed to conduct virology studies on our processed biological extracts (refered to as test samples in our below request write-up) ( read more ).....Closed
09-1907 USA Preclinical Contract Research Organization needed for professional luminex analysis of mice, monkey and human cytokines" ( read more ).....
09--1905 USA GLP Preclinical Contract Research Organization needed for Erythropoietin bioassay-Establish the specific activity of a erythropietin batch. Also interested in in vivo potency assay. We would like to outsorurece this test for future clinical trials. ( read more ).....Closed
09-1893 Preclinical Contract Research Organization needed for Toxicology testing - Het-cam ( read more ).....Closed
09-1892 Non-GLP Preclinical Contract Research Organization needed that has capability and experience with in vitro metabolism studies in liver slices (rat and human). Prefer a lab with its own analyical chemistry capabilities. ( read more ).....
09-1884 FDA Preclinical Contract Research Organization needed to test the combination of Rescula with Alphagan and both compounds separately to look at intraocular pressure (IOP) reduction. We would like to potentially look at other endpoints/markers such as micro circulation, effect on laser induced injury, or others that could especially show some neuroprotective effect in an animal model (rat or rabbit). ( read more ).....
09-1876 Eastern USA Preclinical Contract Research Organization needed that can receive and handle wild caught Norway rats and house mice in order to perform a Blood clotting response test to establish levels of rodenticide resistance to 2nd generation rodenticides in the New York City area. ( read more ).....
09-1875 Europe Preclinical Contract Research Organization needed for In vivo models for Tubercolosis test. The laboratory will be part of a EU grant. Availability for the collaboration is required urgently ( read more ).....
09-1874 USA NCCLS/CLSI EP6-A Preclinical Contract Research Organization needed to collect venous blood samples from 1-2 donors, spike with glucose (up to 600 mg/dL) or allow glucolysis (30 mg/dL). Do linearity testing with 11 glucose levels, 10 reps/level on each of 2-3 home use blood glucose meter systems. ( read more ).....Closed
09-1868 Indiana Midwest FDA Preclinical Research Organization needed to build and validate system for measuring water flow rate over time at low rates (2-10 ml/hr, over several days) and under specific hydrostatic pressures, from -4 to +4mmHg. Pressure measurement must be traceable to NIST standards. ( read more ).....
09-1864 FDA Preclinical Contract Research Organization needed to test the combination of Rescula with Alphagan and both compounds separately to look at intraocular pressure reduction (IOP) reduction. We would like to potentially look at other endpoints/markers such as micro circulation, laser induced injury ?, or others that could potentially show some neruoprotective effect in an animal model (rat or rabbit). ( read more ).....Closed
09-1862 ISO Preclinical Research Organization needed for Sensitization Test as welll as full biocompatibility device testings ( Sensitization Cytotoxicity and Irritation) as per ISO 10993 - need at least three quotes ( read more ).....Closed
09-1857 Australia/Europe/Asia Preclinical Contract Research Organization needed for Medical Devices Biocompatibility Sensitization as per ISO 10993-10 and Cytotoxicity agar overlay method ( read more ).....Closed
09-1826 ECC GLP Preclinical Contract Research Organization needed for OECD Skin Sensitisation Local Lymph Node Assay OECD 429 LLNA Détails woulb be send on contact ( read more ).....Closed
09-1819 US or Europe GLP Preclinical Contract Research Organization required to evaluate the excretion of radioacticity in rat urine feces, bile and blood ( read more ).....Closed
09-1789 Preclinical Contract Research Organization required for testing compound activity vs HCV polymerase (i.e. Replicon assay or antiviralactifity in JFH1 infection model). ( read more ).....Closed
09-1777 California GLP Preclinical Contract Research Organization required for rabbit bioassay for insulin ( read more ).....Closed
09-1770 FDA/GLP Preclinical Contract Research Organization required to test our DNA vaccine for repeated dose toxicity and biodistribution ( read more ).....
09-1767 Preclinical Contract Research Organization required for performing chemotherapy-induced ototoxicity in vivo ( read more ).....Closed
09-1765 India Preclinical Contract Research Organization required for in vitro antidiabetic study to assess efficacy and mechanism of action ( read more ).....Closed
09-1747 FDA GMP Preclinical Contract Research Organization required forperformance testing to support 510(k): Comparative performance testing using crystaloids, whole blood, and Red cell concentrate (RCC's) Need estimate within the week for budget deadline ( read more ).....
09-1746 FDA 510(k) Preclinical Contract Research Organization required for: Medical Device Design and Modelling of Systems Medical Device Compliance Testing Reuseable Medical Devices Testing Medical Devices Methods Development and Validation Testing Medical Devices Transportation Simulation Studies Need estimates within the week for budget deadline. ( read more ).....
09-1743 FDA GLP, ISO, ASTM Preclinical Contract Research Organization needed for: Medical Device Stability Studies Testing Medical Devices Accelerated Aging Stability Studies. Medical Devices Real Time Stability Studies. Need estimates within 1 week for budget deadline ( read more ).....
09-1733 FDA Preclinical Contract Research Organization required - looking for an animal model to test the mechanism of nausea induction by a small molecule GI drug and its major metabolite. ( read more ).....Closed
09-1725 FDA Preclinical Contract Research Organization required for testing an animal model to determine whether a small molecule compound and its major metabolite can induce shortness of breath (dyspnea). ( read more ).....Closed
09-1720 Europe or elsewhere Preclinical Contract Research Organization required - We have produced a glycoprotein that we want to test for its inhibitory effect on oculotropic adenoviruses 8, 19a and 37 and enterovirus 70. In vitro test with above mentioned glycoprotein and viruses labelled with 35S or 3H would be used in cell models such as MDCK and/or Vero cells and HCE (human corneal epithelial) cells. ( read more ).....Closed
09-1684 UK Preclinical Contract Research Organization required for Undecalcified sections of bone with small (3.5x6mm)titanium alloy implant in situ required - ground and polished to 30-50 micron for light microscopy. ( read more ).....
09-1672 California FDA/GLP Preclinical Contract Research Organization required for 2 animal GLP oral safety; GLP efficacy in microbial GI infectious disease ( read more ).....
09-1654 US, Europe Non GLP Preclinical Contract Research Organization needed to test our antiviral products: activity against HCV polymerase activity, HCV replicon and, possibly antiviral activity in the JFH1 infection model" ( read more ).....Closed
09-1652 Europe/Sweden or Denmark preferred EU GMP Preclinical Contract Research Organization required to test three batches of vaginal tablets according to the Ph.Eur. 2.9.2 test disintegration of suppositories and pessaries. ( read more ).....Closed
09-1651 Europe, UK Non-GLP Preclinical Contract Research Organization required for In vitro assessment of the spectrum of anti-bacterial activity ( read more ).....Closed
09-1644 Non-GLP Preclinical Contract Research Organization required to test a formulation for diabetic wound healing in animal model. Also require biomarkers for wound healing. ( read more ).....Closed
09-1626 California Preclinical Contract Research Organization required for testing using rhuses monkey plasma to detect hepatitis A antigen or antibody (both IgG and IgM) ( read more ).....Closed
09-1614 San Diego, California USA Preclinical Laboratory needed for small molecule efficacy testing against influenza viruses H1N1 and H5N1 ( read more ).....Closed
09-1611 USA FDA GLP Preclinical Contract Research Organization needed for acute eye irritation study in rabbits and acute skin sensitization study in guinea pigs of a water-based coolant ( read more ).....
09-1607 Canada Non-GLP or GLP Preclinical Contract Research Organization required for testing modified insulin's function in diabetic animal model ( read more ).....
09-1594 UK, Europe Preclinical Contract Research Organization required to set up a guinea pig tinea pedis (athlete's foot) experimental skin infection model based on Niwano et al (1995) publication. ( read more ).....Closed
09-1581 Preclinical Contract Research Organization required for 90 day inhalation toxicity study in rats with post exposure observation period of up to three months including bronchoalarlavage fluid (BALF analysis (OTPPTS 870.3465 or OECD 413 test guidelines) and data which would help characterize possible adverse effects of exposure to both single wall and multiwall carbon nanotubes. ( read more ).....
09-1577 USA FDA 510(K) Preclinical Contract Research Organization required for testing animal-derived tissue for medical device application ( read more ).....
09-1575 USA GMP/GLP/ISO preferred; must comply with USDA 9 CFR 113.53 Preclinical Contract Research Organization required for testing Adventitious agents ( read more ).....Closed
09-1567 US FDA Preclinical Contract Research Organization required to test for monensin in cattle feed ( read more ).....Closed
09-1558 USA FDA GLP Preclinical Contract Research Organization required to do testing of medical device on tissue culture - Test the response of a variety of cell types (Osteoblasts, osteoclasts and chondrocytes) to sequential variations of a pulsed electromagnetic field signal. ( read more ).....
09-1550 FDA TRO and FCN Toxicology Preclinical Contract Research Organization required for testing chromosomal aberration CHO and mouse lymphoma, two samples each soluble to saturation in DMSO (1% and 3% w/w saturation) ( read more ).....Closed
PK NHP 1 Large Molecule n=3 9 timepoints ship samples ( read more ).....Closed
09-1549 USA NON-GLP Preclinical Contract Research Organization required for PK NHP 1 small molecule n=3 9 timepoints. Ship samples. ( read more ).....Closed
09-1540 USA Preclinical Contract Research Organization required for short term biopersistence test by inhalation - it has been shown that fibers longer than 20 pm have a weighted half life less than 10 days. Related to the EU directive 97/68/EC ( read more ).....Closed
09-1509 USA, Europe or UK FDA Preclinical Contract Research Organization needed for efficacy study using PAH(pulmonary arterial hypertension) induction animal model and hemodynamic measurement (BP, PAP, RVP, PVR...) For your reference, we consider to perform the study in rodent (Rat), if possible. The required specific hemodynamic parametors are pulmonary artery pressure, pulmonary vascular resistance and right ventricle pressure. ( read more ).....Closed
09-1506 USA FDA, AAALAC Preclinical Contract Research Organization required for porcine bariatric models to evaluate the preclinical safety and efficacy of a novel gastric banding device. The general study outline currently under consideration consists of 10 animals (Rx vs control), 90 day in-life phase with daily clinical observations (including weight) followed by necropsy and histopathology of the treatment site. In addition, we have a trained human surgeon (MD, FACS) who specializes in baria ( read more ).....
09-1497 GLP, FDA Preclinical Contract Research Organization needed for cardiovascular monitoring in dogs both awake and anesthetized during a 10-minute drug infusion, several dose levels, and for at least an hour before and after the infusion. Telemetry preferred. ( read more ).....Closed
09-1474 Canada or US Preferred Preclinical Contract Research Organization required for testing of new drugs against RNA viruses in human cell culture - Screening potential new drugs in human cells infected with H1N1 influenza virus, and perhaps against other viruses, particularly HIV ( read more ).....Closed
09-1462 India GLP Preclinical Contract Research Organization required do perform safety study for intravitreal injection in rabbits ( read more ).....
09-1444 USA Preclinical Contract Research Organization required for a conducting a research study with three related tests. 1. Serum Gc-protein level (vit D binding protein) 2. Gc-MAF for quality control (Gc Macrophage activating Factor) 3. serum NaGaLase level = alpha-N-acetylgalactosaminidase reported as mcg/min/mg protein? in literature. ( read more ).....Closed
09-1436 Preclinical Contract Research Organization required for toxicity testing - we would like a biopestide produced by our company subjected to toxicological assessment to include two fish, two birds, earthworms, single celled organism in water (algae or protozoa), bees, Rodents (guinea pig or rat) and mammalian (Dog)to include oral, feeding, skin sensitization and dermal toxicology. Please adice on cost and duration required for these tests ( read more ).....Closed
09-1427 New Delhi India Preclinical Contract Research Organization needed for a project which is a part of my degree course - this may be in clinical or preclinical trial. ( read more ).....Closed
09-1426 Europe GLP, OECD Preclinical Contract Research Organization required for Early Life Stages (Fathead minnow) ( read more ).....Closed
09-1425 FDA, OECD, GLP Preclinical Contract Research Organization required for Amphibian metamorphosis assay ( read more ).....
09-1417 USA-Gulf of Mexico Region Federal Regulations section 173.132 Preclinical Contract Research Organization required to do Toxicology Study - An LC50 for mist inhalation one hour. Animals: Young adult albino rats (male and female). More than 90% of particles of mist must have a diameter of 10 microns or less. LC50 = concentration of the product that causes death to half the population within 14 days of exposure. The product is an industrial biocide/water treatment product (aqueous). ( read more ).....Closed
09-1413 INDIA USFDA Preclinical Contract Research Organization required to test In Vitro Phosphate Binding Assay for Generic Development Product ( read more ).....Closed
09-1404 Preclinical Contract Research Organization needed for preclinical studies with RAT models of lung inflammation. In particular models of inflammation induced by either House Dust Mite (HDM) or Cockraoch Antigen (CRA. ( read more ).....Closed
09-1374 Preclinical Contract Research Organization needed with a rabbit inflammatory arthritis model (e.g. adjuvant induced arthritis) suitable for testing small molecule oral anti-inflammatory. ( read more ).....
09-1373 USA Non GLP Preclinical Contract Research Organization required for in situ intestinal perfusion studies ( read more ).....Closed
09-1348 USA Preclinical Contract Research Organization required for CD40 Ligan testing ( read more ).....Closed
09-1347 USA Preclinical Contract Research Organization required to do Lyme Disease cross anti-myelin testing. ( read more ).....Closed
09-1333 USA GLP Preclinical Contract Research Organization needed to complete the clinical chemistry pathology analysis and the histology analysis of 15 major organs. ( read more ).....Closed
09-1321 USA GMP Preclinical Contract Research Organization required to test Antibiotic Resistance. We have positive cultures in media we use to transport tumor tissue to the lab. The contaminant is from the tissue. We are trying to see what kind of antibiotic would be useful to use in the media or for treating the mice we grow the tumors in for xenografts. ( read more ).....Closed
09-1290 US Standards Preclinical Contract Research Organization needed for Transgenic mice (Tg2576) sAPPalpha studies -Alzheimer's application ( read more ).....Closed
09-1283 USA Preclinical Contract Research Organization requried for performing a small study to document isotherms in vivo for two cryosurgical systems using a porcine model. The cryoablation procedures are generally performed laparoscopically with US guidance or percutaneously with CT or MRI guidance. ( read more ).....Closed
09-1274 Israel ELISA Preclinical Research Contract Organization required for testing for Insulin, GIP,adiponectin in rat. ( read more ).....Closed
09-1255 FDA Preclinical Research Organization required for SPF in vivo 20 person test for a cosmetic product. Looking for best price. ( read more ).....Closed
09-1251 India Preclinical Research Organization needed to do Polymorphism and Isomerism study. ( read more ).....Closed
09-1249 USA Preclinical Research Organization needed for Double Blind Placebo controlled crossover trial, in healthy individuals, one hour's duration, to determine speed of onset for commercially available energy drink. Measurements to include visual analog scales for alertness and energy levels, and measurement of simple reaction times, approx. every 7 minutes, for an hour. ( read more ).....Closed
09-1238 USA FDA GLP Preclinical Research organization needed to analyze Lucentis in both serum and eye components such as vitreous humor in human and monkeys using validated GLP analytical methodology . ( read more ).....Closed
09-1228 USA Preclinical Research Contract Organization required to measure the in-vitro inhibitory effect of mouthwash and/or mouthwash components on alkaline phosphatase activity - Enzyme Inhibition Testing. ( read more ).....Closed
09-1219 Preclinical Contract Research Organization required for testing compounds in Diabetic nephropathy model to determine any protective effect of our compound ( read more ).....Closed
09-1217 UK Preclinical Laboratory needed for lab testing of a cleaning/disinfecting agent against viruses such as Avian flu, Swine flu, SARS, HIV, Polio, Hep B and C. ( read more ).....Closed
09-1208 Preclinical Laboratory needed for preclinical study: ASA in guinea pigs and PCA (passive cutaneous anaphylaxis) in rats ( read more ).....Closed
09-1207 FDA GLP PRECLINICAL LABORATORY NEEDED FOR PASSIVE CUTANEOUS ANAPHYLAXIX TEST (PCA) in rats / mice & ACTIVE SYSTEMIC ANAPHYLAXIS TEST (ASA) in guinea pigs ( read more ).....Closed
09-1202 Europe FDA GLP Preclinical ZToxicology, Contract Research Organization needed for Repeated Dose Inhalation Toxicity: 28-day day Study with additional information on biokinetics The study has to be performed with 3 sizes of cerium oxide of which 2 are <100 nm MAD and sdg<1.5 an a third that contains particles > 100 nm. The test material will be provided by the sponsors via the RIVM. An option to test a third product with a diameter < 100 nm needs to be included in the budget. The default OECD T ( read more ).....Closed
09-1201 Europe FDA GLP Preclinical Contract Research Organization needed for GLP or GLP-like pharmacology efficacy study of a topical formulation for the treatment of Herpes Simplex Virus on rodent models. ( read more ).....Closed
09-1200 Europe FDA GLP Preclinical Contract Research Organization needed for pharmacology efficacy study on androgenetic alopecia. Test the efficacy of a topical formulation on androgenetic alopecia (AGA) rodent models. ( read more ).....Closed
09-1174 Europe or USA Non-GLP, non GMP Preclinical Contract Research Organization needed for preclinical antiviral screening, Antiviral activities in cell culture assays against wild type HBV (HepG2215) and HIV (MT-4). For the secondary screening, resistant strains of lamivudine and AZT. ( read more ).....Closed
09-1157 California Preclinical Laboratory needed for Preclinical Study for Influenza H1N1 vaccine (in rodents and ferrets) ( read more ).....Closed
09-1109 GLP Preclinical Toxicology Laboratory needed for 14-Day Implant Tox Study in Rats with a 7-Day Recovery ( read more ).....Closed
09-1093 US Preclinical CRO needed to ERG measure the oxygen levels in retinas of mice using MRI. ( read more ).....Closed
09-1092 US FDA CRO needed for full preclinical development package for an inhale formulation of a small molecule compound. The compound has already been developed for an oral formulation. Need quote for all necessary studies to proceed into phase 1. ( read more ).....Closed
09-1075 FDA GMP, GLP Preclinical Contract Research Organization needed for QPCR or infectivty testing of a pharmaceutical product for Porcine Circovirus Type 1 (PCV-1). The test must be specific to PCV-1 and not PCV-2. ( read more ).....
09-1070 India FDA GMP Preclinical Medicinal Chemistry, Contract Research Organization needed for Discovery, Design and development of novel drug molecules, Nanoparticles/Microparticles for Novel Drug formulations In that context, I want to have details regarding various types of analyses viz: 1. Invitro Anti TB/AntiHIV activity 2. DNA Binding, DNA cleavage analysis With kind regards, Yours sincerely ( read more ).....Closed
09-1055 USA Preclinical Pharmacology Contract Research Organization needed for herpes in vivo studies - animal testing for herpes treatment ( read more ).....Closed
09-1037 Preclinical needs CRO for preclinical study for promotion of healing and prevention of late stent thrombosis in rabbit iliac model and also for angiogenic response and neovascularization in subcutaneous implant in rat models ( read more ).....Closed
09-0994 USA, Canada Preclinical hematology laboratory needed for testing 30 rat blood testing for Electrolyte balance, carbohydrate metabolism, liver and kidney function. ( read more ).....Closed
09-0968 USA FDA GLP Preclinical CRO needed for GLP preclinical safety and efficacy study of NOVEL PHARMACOLOGIC FOR TREATMENT OF MACULAR DEGENERATION. Animal Model. ( read more ).....Closed
09-0962 Biotech Co needs preclinical CRO for Proof of concept study of allergic rhinitis Design Step one: initial model evaluation (5 mice). If client satisfied with the model, then step two will be initiated. Step two: treatment with ABI-100 (20-40 mice) Study protocol: Model: 5 weeks old female BALB-C mice will be used. On day 0, 7, 14 and 21, mice will be immunized by intraperitoneal injection of 10 ug of ovalbumin (OVA) and 1 mg of aluminum hydroxide (alum) in 300 ul of phosphate-buffered s ( read more ).....Closed
09-0956 Preclinical CRO needed for in vitro study to measure inhibition of statin-like drugs on rat liver HMG coA reductase in vivo ( read more ).....Closed
09-0955 Preclinical CRO needed for in vitro study to measure inhibition of statin-like drugs on human hepatocyte HMG coA reductase in vitro ( read more ).....Closed
09-0951 India Preclinical Laboratory needed for Non-GLP Preclinical Testing in a model which can predict Efficacy of a drug in SCID mice bearing Leukemic cells ( read more ).....Closed
09-0947 FDA GLP preclinical CRO needed of efficacy testing of small molecule compound on a spinal stenosis/neuropatic pain model ( read more ).....Closed
09-0946 Georgia FDA GLP Preclinical Oncology, Contract Research Organization needed for preclinical studies of new laser cancer treatment on bi animals, such as dog or monkey. The method is intravenous injection of nanoparticoes and then use laser to irradiate the tumor and see the tumor shrinkage. We have done mice studies and we need finish the other required tests according to FDA requirement before clinic trials. ( read more ).....Closed
09-0911 USA FDA GLP CRO needed for entire preclinical toxicology study package for a dermal ointment administration of a small molecule (prostaglandin -like compound. Full oral development performed. ( read more ).....Closed
09-0867 USA or Canada preclinical contract research organizaiton needed for conducting preclinical studies to measure the surfactant phospholipid content in the amniotic fluid or fetal lung tissue from the sheep, so as to measure the fetal lung maturity. ( read more ).....Closed
09-0842 Preclinical Contract Research Organization needed for Anti-hepatitis B virus activity in HepG 2215 cell line and the resistant strains lamivudine. ( read more ).....Closed
09-0817 FDA, GMP Preclinical COntract Research Organization needed for small animal proof of concept study with a topical agent for allergic rhinitis that would be acceptable to FDA. If study positive, will require minimum toxicology studies necessary for FDA IND. ( read more ).....Closed
09-0809 FDA Preclinical Contract Research Organization needed with an animal model for dry age-related macula degeneration ( read more ).....Closed
09-0801 Preclinical Contract Research Organization needed for lead identification of chemicals (<10) for their vasodilating properties hopefully using an in vitro model. ( read more ).....Closed
09-0767 USA Preclinical contract research organization needed for testing biological potency of rhG-CSF protein in male 7-8 week old BALB-c mice (19-24g) or appropriate mice. ( read more ).....Closed
09-0735 Preclinical laboratory needed for preclinical toxicology studies for a typhoid fever vaccine: Single-dose toxicity studies Acute toxicity studies in rat and rabbit; intramuscular route Skin sensitisation testing Guinea Pig Maximisation Test Genotoxicity/ Mutagenicity studies Bacterial reverse mutation test (Ames test) In vitro mammalian chromosome aberration test In vitro mammalian cell gene mutation test Reproduction toxicity studies Fertility study Pre- and postnatal developmental study Embryo ( read more ).....Closed
09-0731 Canada FDA GLP Preclinical Toxicology Laboratory needed for Single-dose toxicity studies Acute toxicity studies in rat and rabbit; intramuscular route Skin sensitisation testing Guinea Pig Maximisation Test Genotoxicity/ Mutagenicity studies Bacterial reverse mutation test (Ames test) In vitro mammalian chromosome aberration test In vitro mammalian cell gene mutation test Reproduction toxicity studies Fertility study Pre- and postnatal developmental study Embryo-foe ( read more ).....Closed
09-0724 Eastern Canada Preclinical Laboratory needed for FDA GLP, In-vitro testing: aPTT, PT, ACT and TT performed on pooled plasma spiked with anticoagulant and placebo ( read more ).....Closed
09-0717 Preclinical Contract Research Organization needed for non-GLP, small animal preclinical model of bone fracture healing e.g. rabbit rib fracture model or similar ( read more ).....Closed
09-0710 Greece Pharmaceutical Manufacturer needs preclinical laboratory for antiviral drug testing (HIV,HSV etc) ( read more ).....Closed
09-0669 Preclinical Contract Research Organization CRO needed for BCG vaccine challenge and evaluation study using mice or quinea pig. challenge and evaluation study after vaccination for anti-tuberculosis ( read more ).....Closed
09-0659 Large pharmaceutical manufacturer needs non-GLP preclinical CRO that specializes in models for critical care including myocardial infarction, Sepsis, Acute lung injury and acute kidney inury ( read more ).....Closed
09-0635 China FDA GLP preclinical contract research organization needed for preclinical testing for HCV in vivo model ( read more ).....Closed
09-0618 In need of CRO that can complete CAM asasy and matrigel assay for various nanoparticles samples. ( read more ).....Closed
09-0615 Biotechnology Company needs Europe FDA GLP Preclinical Contract Research Organization for FDA IND. Murine Hindlimb Ischemia Model in immunodeficient animals to test potency of human bone-marrow derived progenitor cells ( read more ).....Closed
09-0583 USA FDA GLP Preclinical Contract Research Organization needed for GLP Surgical Model Study of biologic medical device that will be used in Surgical procedure (vascular and trauma model) to test hemostasis ( read more ).....Closed
09-0574 Asia, North America,or Europe FDA GLP Preclinical Contract Research Organization for IND enabling study to investigate the rates and routes of excretion of total single oral administration of 14C-labeled compounds. We already have 14C-labeled compounds. Would be possible to let us know possible timeline and overall price? We haven't made detail study design. We think the study would be performed in two species (rat and dog), female and male, single oral administration, excretion route feces and ( read more ).....Closed
09-0559 Asia Pharmacogenomics Company needs Asia FDA GLP Preclinical Contract Research Organization for IND enabling study to investigate the rates and routes of excretion of total single oral administration of 14C-labeled compounds. We already have 14C-labeled compounds. Would be possible to let us know possible timeline and overall price? We haven't made detail study design. We think the study would be performed in two species (rat and dog), female and male, single oral administration, excretion ro ( read more ).....Closed
09-0555 USA Preclinical Laboratory needed for in vivo testing of sepsis preferably colon ligation and puncture model in Rodent model of ( read more ).....Closed
09-0554 USA Biologics Company needs USA preclinical contract research organization for Implantation Study. Implant samples into an athymic rat abdominal pouch model for a 28 day duration. After the 28 day duration, I would like to muscle pouch explanted, imaged (x-ray and/or CT), and then histology done to quantify the amount of bone that was formed. ( read more ).....Closed
09-0534 Pharmaceuticals Company needs FDA GLP Preclinical Toxicology Laboratory for 90-day inhalation toxicity test (CFR 870.3465) in rats with special attention to histopathology (inflammation and cell proliferation) of the lung tissues and to various parameters of the bronchoalveolar lavage fluid (BALF), e.g., marker enzyme activities, total protein content, total cell count, cell differential, and cell viability. It is not necessary to look at internal organs. A recovery period of 60 days must be inc ( read more ).....Closed
09-0517 US Preclinical Contract Research Organization needed for Non-GMP, preclinical antibody labeling/biodistribution study in Monkeys or other non-human primate ( read more ).....Closed
09-0488 India Preclinical Immunology COntract Research Organization needed for preclinical study: Delayed type hypersensitivity (DTH) mice or rat model. Expermental autoimmune encephamyolitis (EAE) mice or rat model ( read more ).....Closed
09-0482 Preclinical Laboratory needed for Nonclinical/pre-clinical assessment of TLR-mediated adjuvants ( read more ).....Closed
09-0462 Biotechnology Company needs European Bioanalytical Preclinical laboratory for Fluorescence measurements of a fluorescent drug from plasma samples. Chromatographic separation not necessary, but may be useful. ( read more ).....Closed
09-0456 FDA Non-GLP and GLP preclinical laboratory needed for in vivo neural studies in small animals (medical device, brain surface) ( read more ).....Closed
09-0455 Pharmaceutical company needs Non-GLP Preclinical, Contract Research Organization CRO for evaluation of anti-arthma effects of monoclonal antibody in rhesus monkeys model. ( read more ).....Closed
09-0446 India Lab for In vivo PK/PD/PK..Mechanism of Action,cell line testing,toxicology testing.(preclinical,toxicology,Mechanism of action,in vivo animal..PK/PD/PK ( read more ).....Closed
09-0427 Asia Biopharmaceutical Company needs FDA GLP preclinical CRO contract research organization for preclinical study of influenza vaccine in ferret model ( read more ).....Closed
09-0394 Large pharmaceutical company needs preclinical genetics labroatory for Sequencing of rabbit DNA to find mutant genes ( read more ).....Closed
09-0363 Proteomics Biotechnology Company needs preclinical, oncology Contract Research Organization for Biomarker, Microarray Discovery and development study (proteomics based). We are actually working on a compound able to inhibit a signalling pathway involved in cancer progression. Several pre-clinical trials suggest a possible role of our compound in breast and prostate cancer. The key remaining issue today is to identify a valid PD Marker prior to first administration to man. Would it be possi ( read more ).....Closed
09-0338 Russia Biotechnology Manufacturer needs Europe FDA GLP Contract Research Organization for GLP preclinical studies for an anxiolytic drug that was succesfully developed, registered and applied in Russian Federation. The results of the studies should be valid for an appropriate application file in order to be registered in Europe. ( read more ).....Closed
09-0286 Lab needed for Non-GLP Preclinical study to evaluate the efficacy of a proprietary compound in preventing the renal ischemia reperfusion injury in rat/mouse model ( read more ).....Closed
09-0262 Non-GLP Preclinical Contract Research Organization needed to test our new placebo solution for a clinical study in a complement activation assay. We are looking, for example, for rises in SC5b-9 and Bb, using enzyme-linked immunosorbent assay. ( read more ).....Closed
09-0253 USA GMP FDA Preclinical Research Organization needed for Phase 1 and 2 of FDA clinicals ( read more ).....Closed
09-0246 USA Toxicology Preclinical Contract Organization needed - We have a library of compounds with potential neuroprotection. We are considering pre-screening the library in lower animal model to prioritize them before beginning our rodent studies. Can you provide an estimate for this type of service? ( read more ).....Closed
09-0243 Israel,Europe ISO Preclinical Laboratory needed for cell biology testing: cell attachemnt test (fibroblasts, keratinocytes) NADPH oxidase activity test (monocytes, macrophages) cell proliferation tests. ( read more ).....Closed
09-0239 GLP OECD 473 Preclinical Contract Research Organization needed for toxicity testing by performing an In vitro Mammalian Chromosome Aberration TOxicology Testing for some of our commercial products. In vitro Mammalian Chromosome Aberration Test according to OECD 473OCDE 473 en français OECD 473 in English. The laboratory must be GLP approved (Good Laboratory Practices)The solvent to be used is DMSO The appearance of the product and or of the obtained dilutions should be part of the reportCells: ( read more ).....Closed
09-0215 Preclinical Contract Research Organization needed for animal trial of stenting in small size. ( read more ).....Closed
09-0194 USA non-GLP Preclinical Contract Organization needed for vaccine study including anthrax challenge in small animals, mice or possibly rabbits. ( read more ).....Closed
09-0191 USA FDA, Non-GLP Preclinical Contract Research Organization needed to determine plasma insulin levels in rat plasma samples. Number of samples is approximately 75. ( read more ).....Closed
09-0185 USA Virology, FDA GLP Preclinical Contract Research Organization needed in vitro testing - inhibitory activity of compounds on herpes simplex virus. Initially two samples will likely be used. ( read more ).....Closed
09-0164 Preclinical Contract Research Organization needed for virucidal efficacy study. I am researching the costs associated with testing the virucidal efficacy of a hand wipe that contains microfibers that removes the rhinovirus from hands as a prevantitive for spreading the common cold ( read more ).....Closed
09-0156 Texas, USA GLP Microbiology, Preclinical Contract Research Organization needed to use genetic techniques to detect the presence of various microbial taxa in solutions containing a mixed microbial community. To identify microorganisms down to genera and species if possible. To quantify populations using culture and non-culture techniques. ( read more ).....Closed
09-0149 Eastcoast USA or Norway GMP FDA Compliant Preclinical Contract Research Organization required for in vivo animal testing: mouse LD50 and abnormal toxicity testing needed for (FDA compliant) release testing. Written reports required. CRO should be GMP certified and FDA registered. ( read more ).....Closed
09-0142 UK ISO, GLP Preclinical Contract Research Organization needed to study in vitro toxicology of particles. We have particles of different materials which we would like to compare in their in vitro response. Ideally if there is a ISO test(s). To observe eg. cell contact and any cytokine release. ( read more ).....Closed
09-0141 GLP Preclinical Contract Research Organization needed for efficacy study, toxicology, and product safety testing; Comparability studies between old and modernised topical anti-inflammatory products. Preferred models: UV-induced erythema, carrageenan edema and hyperalgesia, cutaneous irritation, intraplantar irritation, ocular irritation. ( read more ).....Closed
09-0139 GLP, FDA, OECD Preclinical Contract Research Organization needed for multiple dose rabbit and monkey ocular toxicity studies up to 28 days in duration. Draize test scoring, histopathology, CBC ( read more ).....Closed
09-0115 Preclinical Contract Research Organization needed for preclinical efficacy testing anti viral activity vs influenza. ( read more ).....Closed
09-0109 Pharmaceuticals, Preclinical COntract Research Organization needed to detect and measure and extract the bio-synthesized compounds from cellular gene mutation as a result of programmed cell death in vivo from the roots of a living plant? It would necessarily need to be in a similar growing environment as opposed to a lab specimen. ( read more ).....Closed
09-0095 North America FDA GMP, GLP Preclinical Contract Research Organization needed for cell proliferation testing for release and characterization. ( read more ).....Closed
09-0065 CaliforniaFDA GMP Preclinical Contract Research Organization needeed for Single-Dose Acute Toxicology Studies of Metabolite analysis of "hot" radiolabled peptide ( read more ).....Closed
09-0047 West Coast USA Preclinical Contract Research Organization needed to perform PBMC isolation for upcoming phase III clinical trials. ( read more ).....Closed
08-2639 USA Preclinical Contract Research Organization needed for animal study on a molodable bone void filler material to support its use to fill neurosurgical burr holes and craniotomy cuts. The data from the study would support an FDA submission and documentation for other regulatory agencies. The model that has been successfully used is a rabbit calvarial defect model. ( read more ).....Closed
08-2611 Preclinical Dermatological Contract Research Organization needed for studies on the inhibition of metalloproteinases and anti-wrinkle ability of a specific cosmetic serum. For this, I will like to test the ability of the seum to inhibit the principles MMPS and some other biological tests available. ( read more ).....Closed
08-2591 USA FDA 1999 Preclinical Laboratory needed for testing the effectivness of an alcohol based gel hand sanitizer aganist the norovirus. I already have testing against the FDA monograph, I just need in vitro time kill for the norovirus. If you have capabalities for this please send me details including pricing. ( read more ).....Closed
08-2584 China Preclinical Laboratory needed to conduct the testing and analysis the content of Mosquito Repellent Patch ( read more ).....Closed
08-2575 USA, Europe Preclinical Laboratory needed for testing glaucoma model in rats. ( read more ).....Closed
08-2567 WestCoast USA Preclinical Laboratory needed for surface tension measurements of a Contact Lens cleaning solution to show cleaning efficacy of the solution. ( read more ).....Closed
08-2536 India GLP Preclinical Laboratory needed for testing antioxidant invivo,invitro myocardial infarction. ( read more ).....Closed
08-2521 Virgina Preclinical Laboratory needed for Antibody testing for human parasitical infection with Sparganosis (Spirometra). ( read more ).....Closed
08-2512 GLP, FDA, EU Preclinical Pharmaceuticals, Toxicology Laboratory needed for Chronic Toxicity Testing: 39 weeks toxicity study in monkeys(with toxicokinetics) 26-weeks Toxicity Study in Rats (with toxicokinetics) ( read more ).....Closed
08-2487 USA GLP Preclinical Laboratory needed for performing toxicity studies in marmosets. ( read more ).....Closed
08-2476 USA TFM Preclinical laboratory needed for testing on OTC topical antiseptics - Time-kill, MIC and in vivo (clinical trial). ( read more ).....Closed
08-2439 Europe Preclinical Research Laboratory needed for Growth hormone levels measurement from mouse serum by RIA method. ( read more ).....Closed
08-2418 Philippines, Singapore, India, China, Australia, Thailand GMP Preclinical Laboratory needed for teratogenicity testing. ( read more ).....Closed
08-2413 New Jersey Preclinical Laboratory needed for Rodent In vivo gamma radiation study. We want to irradiate rodents with gamma rays, treat them for about a month and then remove their brains for assay at our labs. Can you help with this experiment? ( read more ).....Closed
08-2387 Canada Preclinical Laboratory needed for specified brain sites to be testing of frozen rat and mouse brains Sectioned brain tissue, micropunched and dissected specified brain sites, store in sterile tubes. Option to return frozen tissue or if you can process them further for DNA analysis to be done by another lab. ( read more ).....Closed
08-2372 Australia Preclinical laboratory needed for lab rat studies - regards Dopamine release - by a medical device - due for FDA testing in 3 years - approximately 2011. I have preliminary studies to confirm Dopamine release - and have US Contacts to support the study. The Labrat studies are intended to be population studies to determine % population effected by the Dopamine release - and dose ranges for co-administration of betablocker - with lab rat longevity analysis to confirm - anti-ageing effect ( read more ).....Closed
08-2360 UK Preclinical Laboratory needed to access a mouse model to test a new anti-MRSA treatment. ( read more ).....Closed
08-2345 Korea Preclinical research laboratory needed to conduct "cartilage defect model efficacy study using immuno-compromised Rabbits for 16 weeks (or 24 weeks)". ( read more ).....Closed
08-2334 USA Non-GLP Preclinical laboratory needed for ITC on antiviral drugs for treatment against HCV. ( read more ).....Closed
08-2331 Hong kong/Singapore/France/USA GMP, HACCP and ASTM Preclinical Food Testing Laboratory needed for Sensory test: preference test for ready to eat frozen pork, shrimp, chicken etc. This result supports the new product development. ( read more ).....Closed
08-2329 France/Germany/Spain/Switzerland GLP Preclinical Laboratory needed for toxicologic package. ( read more ).....Closed
08-2328 Eastcoast USA or Norway FDA GMP Preclinical Laboratory needed for GMP stability testing, pre-marketing analysis, consumer studies. ( read more ).....Closed
08-2237 USA FDA GLP Preclinical Contract Research Organization needed for Alzheimers small molecule efficacy study on nonhuman primate model for Alzheimers disease to test efficacy of a small molecule compound (oral administration). ( read more ).....Closed
08-2224 USA/Europe GLP Preclinical laboratory needed to test repeat dose toxicity: 6 months rodent, 9 months non rodent ( read more ).....Closed
08-2212 Netherlands preclinical laboratory needed to test Croton oil induced pustular dermatitis model in rat. ( read more ).....Closed
08-2211 Netherlands Preclinical Laboratory needed to test P. acnes induced abscess model in rat. ( read more ).....Closed
08-2204 USA/Europe Preclinical Contract Research Organization needed for efficacy study on therapeutic for chronic myelogenous leukemia(CML); we are looking for a CRO who can conduct an efficacy study using T315I cell lines. ( read more ).....Closed
08-2163 FDA GLP Contract Research Organization needed for preclinical testing of a peptide endogenous in human blood normally at high levels. Much published data is available including Pharmakinetics. Idealy we would want the testing laboratory to take on some of the risk taking. The project has extremely good prospects. ( read more ).....Closed
08-2150 USA FDA GLP, GMP Analytical Chemistry Custom Synthesis needed for discovery to IND preclinical formulations development for small molecules ( read more ).....Closed
08-2148 USA FDA GLP Preclinical laboratory needed for Immunohistochemistry staining on provided tumors. Tumors would need to be prepared into sections on fixed by either methanol or ethanol on slides and stained with antibodies against oncology and angiogenesis drug tartets (CD31, CXCR4, EGFR, PDGF, VEGF, etc) ( read more ).....Closed
08-2106 USA, Australia Preclinical Contract Research Organization needed for study with surgical wound infection model - rabbit, guinea pig or mouse, preferably S. aureus but other bacteria would be feasible. Model needs to have been previously established with example data available ( read more ).....Closed
08-2096 Preclinical efficacy testingof new therapeutic agents in animal model of allergic rhinitis ( read more ).....Closed
08-2094 Preclinical Contract Research Organization needed with models of pulmonary arterial hypertension ( read more ).....Closed
08-2067 India preclinical contract research organization needed for recomobinant product expression in CHO cells. Test No 1:HCP content Test No 2: BioAssay ( read more ).....Closed
08-2055 UUS Preclinical Contract Research Organization needed to conduct Non-GMP, Non-GLP In-Vitro Oncology Study of cancer cancer chemoprevention Induction of quinone reductase (QR) activity in cultured murine Hepa 1c1c7 cells (Reference 1). The quinone reductase activity will be assayed by the menadione coupled reduction of a tetrazolium dye. 1. Prochaska H, Santamaria A, Talalay P. Rapid detection of inducers that protect against carcinogens, Proc. Natl. Acad. Sci, 89, pp 2394-2398 (1992). ( read more ).....Closed
08-2047 Preclinical Contract Research Organization needed for experimental testing of human serum samples for fatty acid concentrations (DHA and EPA) in the course of an experiment on coronary artery disease. However, I need to find someone with expertise in this area to perform the gas chromatography and analysis. Does your company provide any chromatography services of this kind? Do you have experience with detection of these compounds? What is the price for the analysis? If not, do you know of anyone ( read more ).....Closed
08-2041 Preclinical Contract Research Organization needed for Preclinical Study for Coombs testing on direct and/or indirect for monkeys ( read more ).....Closed
08-2040 Preclinical Contract Research Organization needed for Preclinical Study on Traumatic brain injury animal model, rodent and/or nonrodent ( read more ).....Closed
08-2032 USA PRECLINICAL CONTRACT RESEARCH ORGANIZATION NEEDED FOR PRECLINICAL TESTING ON RECONSTRUCTED HUMAN SKIN ( read more ).....Closed
08-2029 Asia preclinical Contract Research Organization needed for anti microbial screening, anti diabetic, cytotoxicity MTT ASSAY ( read more ).....Closed
08-2014 USA, EU preclinical laboratory needed for animal efficacy model testing (antibacterial drug): endocarditis ( read more ).....Closed
08-2010 Preclinical Contract Research Organization needed for Non-GLP bioanalysis of a compound (small molecule) in rat plasma and liver. It is a non-GLP study ( read more ).....Closed
08-2003 Asia Preclinical contract research organization needed to conduct preclinical studies on non human primates ( read more ).....Closed
08-1987 USA Preclinical laboratory needed for cell base assay inflammation (TNF alpha, cytokines..)testing ( read more ).....Closed
08-1969 USA Preclinical Laboratory needed for RIA for rat T3 T4 and TSH from serum ( read more ).....Closed
08-1964 Australia, USA or Europe FDA GLP Preclinical Contract Research Organization needed for Acute Inhalation and Oral toxicology on Biological product active ingredient (fungal spores). A clearance study of the organism is required. ( read more ).....Closed
08-1963 Preclinical Laboratory needed with a comprehensive list of all RAT models of inflammation available. For example rat lung inflammation models are most often (almost exclusively) run in Brown Norway rats, what kind of models can we contract to have performed(OVA/alum, allergen or antigen-induced lung inflammation models)? I am also interested in rat colitis models. There are several I am aware of such as, DSS, NTBS, oxazalone and an adoptive transfer model using RB45hi cell. Others? Finally I am ( read more ).....Closed
08-1955 USA FDA GLP or Non-GLP Preclinical Contract Research Organization needed for tissue biochemistry assays for evaluation of acyl CoA oxidase and/or carnitine palmitoyl transferase in liver from rats and nonhuman primates ( read more ).....Closed
08-1932 USA Preclinical, Bioanalytical Contract Research Organization needed for Non-GLP Quantitative GC-MS analysis of DMSO in human blood ( read more ).....Closed
08-1931 FDA Preclinical Non-GLP Contract Research Organization needed for Non-GLP Study on induced spesis in mice ( read more ).....Closed
08-1926 EU preclinical laboratory needed for assaying the stability of small molecules in the plasma ( read more ).....Closed
08-1916 FDA GLP preclinical contract research organization needed for GLP Efficacy testing of drug combination on 80 rats, 1 day follow-up ( read more ).....Closed
08-1915 UK Non-GLP preclinical immunology contract research organization needed for in vivo experiments in mice involving immunisations with prototype vaccine adjuvants and marketed vaccine products with measurement by simple ELISA or ELISOPT assays" ( read more ).....Closed
08-1904 USA, Europe FDA GLP Preclinical Contract Research Organization needed for GLP Study for Local Lymph Node Assay in mice to test the sensitization of the skin to the formulation compounds ( read more ).....Closed
08-1886 USA, Canada FDA GLP preclinicalContract Research Organization needed for PK, Pharmacokinetic studies on a liposomal formulation. Past experience with liposomes is required for the CRO. ( read more ).....Closed
08-1863 USA FDA preclinical contract research organization needed for conducting preclinical CRO study for glaucoma argon-laser induced monkey model ( read more ).....Closed
08-1821 USA or Canada Preclinical Contract Research Organization needed for in vitro pharmacology, In vitro testing for Monoamine Oxidase A & B inhibition, In vitro testing for nicotinic acetylcholine receptor binding/interaction ( read more ).....Closed
08-1802 USA, Europe Non-GLP Preclinical Contract Research Organization needed for Non-GLP Anxiety Study in rats using elevated plus-maze or fear-potentiated startle with 1 compound, 3 test doses and positive control. ( read more ).....Closed
08-1788 Preclinical Contract Research Organization needed for preclinical study of diabetic neuropathy model and do you measure nerve conduction velocity? ( read more ).....Closed
08-1785 FDA GLP Preclinical Contract Research Organization needed for GLP toxicology study; 2 test articles for a rat 28 day study. ( read more ).....Closed
08-1764 Europe, USA, FDA GMP Preclinical Contract Research Organization needed to study persistent epithelial defects using alkali-induced (NaOH) burns or viral models (Herpes) in pigs, guinea-pigs or rats. ( read more ).....Closed
08-1722 USA GLP Preclinical Contract Research Organization needed for irradiation of Non-human primate survival with 5-7.5 Gy ionizing radiation followed by survival studies with blood draws ( read more ).....Closed
08-1710 Europe or US preclinical contract research organization needed for antiviral compound potency against Hepatitis C virus in replicon assay ( read more ).....Closed
08-1689 Preclinical Contract Research Organization needed for in vivo or intro proof of concept on dry eye syndrome with novel eye drop solutions. ( read more ).....Closed
08-1687 USA Preclinical Contract Research Organization needed for Antiviral (Influenza) Testing (both cGLP and non-cGLP) by intratracheobronchial and intranasal instillation. Testing of formulations for antiviral efficacy in animal models by intranasal and intratracheobronchial instillation ( read more ).....Closed
08-1679 Preclinical Contract Research organization needed for testing the binding affinity of ligand to the Melatonin receptor binding assay 1 and 2 ( read more ).....Closed
08-1668 USA Preclinical Contract Research Organization needed for validation of a novel compound for atopic dermatitis for CRO services which can conduct preclinical validation studies in an animal model of atopic dermatitis to determine efficacy of a novel compound. ( read more ).....Closed
08-1663 USA Preclinical Laboratory needed for Platelet aggregation assay and Thromboxane B2 synthesis assay required on medical food product ( read more ).....Closed
08-1657 FDA, Non-GLP Preclinical Laboratory needed for tissue cross-reactivity study. Non-GLP analysis of the 32 FDA-required normal human tissue panel. Costs required for 1, 2 and 3 donors, including method development studies. I would also be interested in obtaining a quote for a full cynomolgus monkey tissue cross-reactivity study. ( read more ).....Closed
08-1645 Canada Preclinical laboratory need for pharmaceutical efficacy testing in small animal on new herbal product administration of a high fat,high cholesterol semi-synthetic diet supplemented with different doses of the test compound for 28 days ( read more ).....Closed
08-1644 Preclinical contract research organization needed for performing DTH assay (delayed type hypersensitivity). We would like to assess whether our compound inhibits a DTH response. ( read more ).....Closed
08-1643 Preclinical laboratory needed to determine whether our compound can inhibit infection of DC-SIGN expressing cells by Mycobacterium tuberculosis. (in vitro TB infection assay) ( read more ).....Closed
08-1640 US or Europe FDA GLP Preclinical Laboratory needed for Coombs assay for Rat ( read more ).....Closed
08-1639 US FDA GMP Canada Preclinical Contract Research Organization needed for testing to determine pharmaceutical equivalence and bioequivalence of several generic oncology drugs for market in the U.S. and U.K. ( read more ).....Closed
08-1634 USA Preclinical Bioanalytical Laboratory needed for Insulin formulation screening by PK and PD, blood glucose in Beagle dogs or Yorkshire Pigs ( read more ).....Closed
08-1621 Europe Preclinical Contract Research Organization needed for preclinical, Proof-of-concept Study for Animal model of contrast-induced nephropathy (contrast agent nephrotoxicity) for testing new drug therapy ( read more ).....Closed
08-1618 USA, UK, Ireland, Canada FDA GMP Preclinical Contract Research Organization needed for BP Pharmacological equivalence study ( read more ).....Closed
08-1570 Preclinical bioanalytical laboratory needed for In-vitro Permeability testing and Cytochromescreen for two chemical compounds ( read more ).....Closed
08-1549 Non-GLP preclinical contract research organization neeeded for proof of concept study to conduct time kills study with either HPV or its surrogate- Simian virus. This is on GLP, and for proof of concept testing with a new antiseptic product. Testing protocol would be developed from existing literature. ( read more ).....Closed
08-1548 Preclinical laboratory needed for in vitro and/or in vivo efficacy tests for anti-rheumatoid arthritis ( read more ).....Closed
08-1547 Preclinical laboratory needed for in vitro and/or in vivo efficacy tests in rare immune disease model like "Crohn's disease", "ulcerative colitis", "lupus", "Hashimoto's thyroidism", "severe combined immunodeficiency" etc. ( read more ).....Closed
08-1546 Preclinical Laboratory needed for in vivo efficacy tests in bone fracture animal models in vivo efficacy tests in "diabetic" and "osteoporosis" bone fracture animal models (2) in vivo efficacy test in rare bone disease animal model like "Osteogenesis Imperfecta" and "fragilitas ossium" etc ( read more ).....Closed
08-1545 Preclinical laboratory needed for in vitro or in vivo HAV efficacy testing ( read more ).....Closed
08-1485 Preclinical Contract Research Organization needed for antiviral testing of our few new derivatives, our parent compound is antiviral against influenza A virus we want to know the activity of our new derivatives against the influenza A virus as well as H5N1 ( read more ).....Closed
08-1472 Preclinical Contract Research Organization needed for preclinical study with animal model for overactive bladder. The model should be in a higher species (mini pig etc.). The model should be based on aberrant C-fiber activity, e.g. a formalin induced OAB. Read-outs are typical cystometry data (mictuition volumes, intercontraction interval etc.). Current medication should show an effect in the model." ( read more ).....Closed
08-1457 USA Non-GLP Preclinical laboratory needed for Testing of General Human TGI xenografts via IP of test agents in a 25 gram mouse. ( read more ).....Closed
08-1450 Preclinical product safety contract research organization needed for PK/PD Animal studies with experience in testing oral delivery mechanisms (tablets in particular) in a relevant animal model. We would like to determine PK/PD of drugs in our proprietary tablet technology. ( read more ).....Closed
08-1446 USA Preclinical laboratory needed for Efficacy Testing of Veterinary Biologics vaccination and challenge of swine ( read more ).....Closed
08-1416 USA Preclinical laboratory needed for NF-kB binding ; NF-kB activation ; quantitation of NF-kBPerform High quality NF-kB inhibition by test agents, using enzyme-linked assay. or DNA binding. ( read more ).....Closed
08-1396 China FDA GLP Preclinical laboratory needed to provide an animal or an in vitro model to test the hydratating action of our product on mucous membrane ( read more ).....Closed
08-1383 FDA GLP Preclinical contract research organization needed for GLP preclinical testing in (in vivo-animal) model able to mimic the Aphtha/mouth ulcer ( read more ).....Closed
08-1370 FDA GLP Preclinical contract research organization needed for GLP preclinical testing in (in vivo-animal) model able to mimic the herpetic keratoconjunctivitis. ( read more ).....Closed